Is a new weight-loss drug making people fall out of love?

Some people using retatrutide, which is not yet approved, are reporting ‘emotional flattening’, but experts point to a more complex picture

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A recent TikTok video shows a man in a black baseball cap, with text over the video stating: “strange effects of Reta” and “ruining relationships”.

He is referring to retatrutide, an experimental weight-loss drug that targets three appetite-related hormones. It is still in clinical trials but has generated such interest that some users are already sourcing it illegally online before approval. The “weird theory going around”, the TikTok poster says, is that the drug can “make you fall out of love”.